Spastic paraplegia four (SPG4; often known as SPAST-HSP) is characterized by insidiously progressive bilateral reduce-limb gait spasticity. More than 50% of afflicted men and women have some weakness while in the legs and impaired vibration feeling at the ankles.?? ????? ???? ??? ???? ?? ??? ? ?? ???? ??? ? ????. ?? ????? ??? ????? ??? ???? ?? ????